12/12/2023 0 Comments Side effects of statins and grapefruit![]() Effects of grapefruit juice on the pharmacokinetics of sildenafil. Grapefruit juice inhibits the metabolic activation of clopidogrel. A report of the American College of Cardiology/ American Heart Association Task Force on clinical practice guidelines. ![]() 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol. Delayed effect of grapefruit juice on pharmacokinetics and pharmacodynamics of tacrolimus in a living-donor liver transplant recipient. Clinical Pharmacology and Therapeutics.įukatsu, S., et al. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: Possible role of organic anion transporting polypeptides. Phase 1 studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients. ![]() Interaction between cyclosporine and grapefruit juice requires long-term ingestion in stable renal transplant recipients. They may recommend a statin that doesn't interact with it or offer other management tips. Talk to your healthcare provider if you take a statin and love grapefruit products. And still, some believe there’s no need to avoid moderate intake of grapefruit products. Others suggest managing this interaction by lowering the statin dose or avoiding large amounts of grapefruit juice. Some experts think avoiding grapefruit juice with statins is best. Statins that aren’t known to interact with grapefruit include rosuvastatin (Crestor), pravastatin, fluvastatin (Lescol XL), and pitavastatin (Livalo).īut it’s not clear how risky the interaction between grapefruit and statins is. The statins most affected by grapefruit are atorvastatin (Lipitor), lovastatin, and simvastatin (Zocor). This can lead to more statin side effects, like muscle pain and possible muscle breakdown ( rhabdomyolysis). But grapefruit and grapefruit juice can increase the levels of certain statin medications. Statins are first-choice options for treating high cholesterol.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |